Noninvasive Blood Glucose Monitor

Our device measures blood glucose optically through the EARLOBE without the need for a blood sample (finger prick).

Valoa has a unique technology for non-invasive blood glucose monitoring.

Valoa’s noninvasive blood glucose monitoring technology is protected by US and international patents and patent applications.

Individual calibration with durability has been demonstrated. Ten test subjects were measured for two days each, a PLS model for each subject was established on Day 1 data and then applied to Day 2 data. The 579 data pairs of Day 2 yield a correlation between the blood-test measured blood glucose and the device result of 0.593, a Mean Absolute Relative Deviation (MARD) of 19.7%, with an extremely statistically significant p-value of 8·10-44. Original article here.

These results should actually have been better; read the report here.

The need for individual calibration would make for an unsatisfactory product. Therefore, Valoa is developing a universal calibration that will allow anybody to use the device straight out of the box. Some restrictions will apply, such as a minimum and a maximum earlobe thickness. It is estimated that about 90% of the general population will be able to use the device.

TechConnect Inovation Award 2019

A universal calibration developed by machine learning using 1239 data pairs obtained on 9 test subjects was tested by applying it to a test set of 248 data pairs obtained from 4 different test subjects. None of these test subjects’ data is in the training set. The correlation between the blood-test measured blood glucose and the device result in the test set is 0.509, an MARD of 23.8%, with an extremely statistically significant p-value of 6·10-18. One measurement in the training set had to be rejected because of movement artifact. In the test set, there were no rejections and all data that was measured was used.

Based on these results, Valoa believes that a universal calibration is achievable.

The technology is available for licensing.

Patents and patent applications for a non-invasive blood glucose monitor are available for licensing.